Preheat the oven to 350 degrees F.
Lightly grease a 12-cup muffin tin with butter.
In a large bowl, combine flour and milk, blending with a rubber spatula. Add the sugar and mayonnaise, and stir until just combined. Spoon batter into prepared muffin tin. Bake for 12 to 15 minutes, or until golden brown.
Recipe courtesy of Paula Deen