Mix butter, chili powder, cumin, brown sugar, orange zest, 1 tablespoon salt and 1 teaspoon pepper together in a bowl. Add the beef, toss to coat evenly. Cover and refrigerate for 1 hour.
Prepare a grill with high heat. Thread the beef, onions and peppers onto 8 long skewers, leaving 1/4-inch space between the meat pieces. Lightly brush grates with oil. Arrange skewers on grill; grill, turning until the meat is medium-rare each side, about 2-3 minutes on each of the 4 sides. Transfer to platter; serve with Bush's® Texas Ranchero Grillin' Beans®.