Preheat the oven to 350 degrees F. Line a 13- by 9-inch cake pan with foil, leaving a 2-inch overhang on two sides. Spray with nonstick spray.
Add the pretzels to bowl of a food processor and pulse until they reach a crumbled coarse crumb texture.
Add the pretzel crumbs, butter and sugar to a bowl and toss all together. Mix and stir to combine. Press into the bottom of the prepared baking dish. Evenly sprinkle the chocolate chips, peanuts, potato chips, toffee and peanut butter chips evenly over the crust. Top with the sweetened condensed milk. Bake until golden brown, about 25 minutes.
Let cool completely. Then lift out of the pan, cut into squares and serve.