Start fueling up at South Carolina’s Caribbean cantina, Fuel Charleston, where locals swear by the jerk chicken sandwich. Stop by Tybee Island near Savannah, Georgia, where crab comes by the platter, piled high with other tasty Georgia shellfish. Then, travel all around Florida’s coastline where you can sample everything from BBQ to Cuban cuisine.

1. Fuel
Guy's trip to South Carolina was a "vacay" from Southern comfort food when he visited Fuel Cantina. Once a gas station, Fuel now boasts an eclectic patio with a Caribbean-inspired menu of spicy island flavors. Taste for yourself with the fiery jerk chicken sandwich or fall-apart pork tacos.

2. The Crab Shack
With a decor that says pirate hangout, The Crab Shack opens its doors to a full-on crab fest 7 days a week, 362 days a year. Rachael ordered "sweet as the South" blue crab, but if you're with friends, feast on the Shack Specialty made with an overflowing pile of crawdad, crab, corn, shrimp and more.

3. Blackwater Grill
For a tried-and-true sea-to-table restaurant, Guy couldn't miss Blackwater Grill on Georgia's St. Simons Island. The local catch, grouper, doubles as the signature with its creamy daufuskie sauce. Even with local seafood, the menu heads south for Cajun faves like spicy gumbo and shrimp and grits.

4. Beachcomber BBQ Grill
Alton's Georgia roots get the best of him during the holidays, and for him, nothing says "holidays" more than barbecue at Beachcomber BBQ & Grill. Beachcomber has no secret ingredient. It's just pure pork, roasted low and slow. From the slaw to the fries, Alton usually orders, well, everything.

5. Sailfish Marina
Since 1952, Sailfish Marina and Resort has served as a refueling stop for sailors looking to catch a bite. With one taste of the Mexican-style yellowtail snapper (sourced from its very own dock) Bobby was hooked. Come nighttime, it's all about the music, sunsets and addictive conch fritters.

6. La Goulue
Almost by accident, Alex discovered La Goulue's cheese souffle. Served since 1973, the signature dish satisfies on all "ooze factor" levels with its gruyere cheese and light-as-air texture. For a classic French dish, try the escargots served with fresh garlic and butter that's perfect for dunking.

7. Larios
When Rachael visited Miami for $40 a Day, she had to order the signature Cubano sandwich at Gloria and Emilio Estefan's restaurant, Larios (she promised Gloria she would). The menu's filled with authentic Cuban favorites like Masitas de Puerco, and the fresh ceviche has a rhythm all its own.

8. Prime One Twelve
Although Prime One Twelve is known for its decadent Kobe beef hotdogs and steak tartare, Chris Santos visits this Miami steakhouse for its Peanut Butter S'more. Made with chocolate and peanut butter ganache that's topped with torched marshmallow cream, the dessert has "s'more" written all over it.

9. The Oyster House Restaurant at Miller's World
For a true Everglades experience, Bobby turned to the Oyster House Restaurant. Located across from the Everglades National Park, the Oyster House has a way with oysters and crabs. But seeing as it's smack-dab in swamp country, they have a way with perfectly preparing frog legs and gator too.

10. Alpine Steakhouse
The Alpine Steakhouse is famous for one thing: turducken. Guy found this place on Triple D, but added it to The Best Thing I Ever Ate. The turducken begins with turkey. Then andouille sausage, duck, chicken, and much, much more are added. Twelve hours in the oven and you have the king of all birds.

11. Crabby Bill's Seafood
Crabby Bill's has been serving the Gulf Coast everything from blue crab to mahi mahi to steamer buckets for more than 30 years. But when Heat Seekers Aaron Sanchez and Roger Mooking visited, they turned up the spice with the volcano gator bites that come with a "deadly zing" ghost chili pepper mayo.

12. Bern's Steakhouse
The steak at Bern's has become legendary, and the recipe is simple: steak, butter, salt and pepper. Five weeks of aging helps, too. But on The Best Thing I Ever Ate, Alex and Sunny duke it out for Bern's most magical dish. Steak or a chocolate peanut butter truffle? Here's a hint -- just get both.

13. Café Tu Tu Tango
Rachael's perfect end to her Orlando trip came from Cafe Tu Tu Tango's ginger sweet potato salad paired with cured pork tenderloin. The menu takes a cue from Barcelona, Spain, with budget-friendly tapas and tasty regional dishes like fried alligator. Live entertainment and local art is on the house.

14. Singleton Seafood Shack
Singleton Seafood Shack has Cajun fried shrimp, steamed shrimp and even shrimp burgers (and the seafood's so local you can hear the boats pull up). But Guy's Diners, Drive-Ins and Dives trip saw another side to the shack with The Sheepshead signature fish, perfectly grilled with Singleton's own blackening spice blend.